is this a flight safe

is this a flight safe?
ok, im not worried about it crashing or anything, but rather is it safe to switch airline companies from U.S. Air to American Airlines. will they lose my luggage? is this a higher risk. well here is a picture of what my flight path would be. and i spaced pleanty of time in between flights just in case a flight is late. http://www.onetravel.com/Default.aspx?tabid=1919&sid=2&oa=BUF&da=SFO&adt=1&chd=0&snr=0&infl=0&infs=0&dd=04-14-2011&tt=ONEWAYTRIP ^^thats the link if anyone wants to find me a better deal. and i need to land in SF late at night and try to keep it under $300. thanks so much, this is really going to help me US Airways Flight 3570 CRJ Buffalo (BUF) New York LaGuardia (LGA) More information 11:10am -14Apr, Thu 12:26pm -14Apr, Thu Nonstop Coach 1hr 16min Operated by US AIRWAYS EXPRESS-AIR WISCONSIN American Airlines Flight 753 S80 New York LaGuardia (LGA) Dallas Fort Worth (DFW) More information 02:40pm -14Apr, Thu 05:40pm -14Apr, Thu Nonstop Coach 4hr 0min American Airlines Flight 1575 738 Dallas Fort Worth (DFW) San Francisco (SFO) More information 09:15pm -14Apr, Thu 11:00pm -14Apr, Thu Nonstop Coach 3hr 45min Flight Duration : 9hr 01min Layover Time : 5hr 49min Total Trip Time: 14hr 50min $ 238 +21 = $259 Total Inc l. fees exc l. taxes Click here to BOOK now & SAVE $ 5 on this flight ¹
Air Travel - 3 Answers
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1 :
Ok, if i'm understanding this correctly, this is a multi-airline trip under ONE ticket, and not just separate routes. First, the airline will rarely lose your luggage when switching airlines because in all actually, the other airline is just another gate. And the link is expired
2 :
You'll most likely be fine, but the more times your luggage is transferred, the more likely it is to be lost or delayed. The chances are very small that your luggage will be lost, but more likely than if you had just one non-stop flight.
3 :
There is plenty of time to allow the bags to transfer so I would not worry.